HHV-6 (Roseola infantum) HHV-8 ( Kaposi’s sarcoma. Herpes zoster ophthalmicus is a reactivated infection of the eye caused by the varicella-zoster virus, the virus that causes chickenpox and shingles . Otoscopy; Neuro exam focusing on Cranial nerve, crossed findings, upper and lower motor neuron involvement; Management. Stress can really sap your energy. [1] Two to four days before the rash occurs there may be tingling or local pain in the area. The rash and blisters associated with shingles can be highly uncomfortable. Abstract. DuraRidge Storm Cloud Hip and Ridge Roof Shingles (20-lin ft per Bundle) Model # 724582. Shingles (Herpes Zoster) vs. It is caused by the varicella zoster virus, which is the same virus that causes chickenpox. Herpes simplex virus (HSV) Infectious mononucleosis. This is the same virus that causes chickenpox. Opioids can cause side effects such as: A mild dizzy feeling. g. Shingles, or herpes zoster, is caused by the Varicella zoster virus. Funds go solely to hosting and development costs that allow medical practitioners around the globe to freely access WikEM. Contents. “There’s usually much more. That way, you don’t feel as much pain. Trigeminal herpes zoster is a potentially devastating clinical occurrence, and is associated with severe long-term neurological sequelae, including encephalitis, vision loss and postherpetic neuralgia. This reactivation causes shingles, typically characterized by the development of a severe rash. These can include essential oils, cold. Shingles and herpes both develop due to herpesviruses. Feels very sensitive to the touch. Clinical Features. Lidocaine 5% is a prescription medication. Varicella zoster virus Varicella (Chickenpox)Some studies reveal that stress causes the shingles virus to reactivate. 97. Individuals who are severely immunocompromised due to immunosuppressive conditions. Gentiana scabra. Most common adult vaccines are. Vesicles within external ear canal and on auricle. muscle aches. Postherpetic neuralgia (PHN) is a complication of shingles infection (also called herpes zoster). Varicella (Chickenpox) Herpes zoster (Shingles) Herpes zoster ophthalmicus. Erythema and Swelling of auricle. Herpes zoster is a painful, unilateral vesicular eruption, which occurs in the dermatome, innervated by the ganglion in which reactivation occurs [ 1 ]. Bell's palsy is also known as. Shingles can lead to serious complications involving the eye, including vision loss. An antiviral medication can: Reduce the amount of time that you have a shingles rash. Shingles, known by its medical name herpes zoster, presents as a painful rash. Pastes. Oatmeal baths. Herpes zoster, commonly known as "shingles," is a viral disease that causes a painful skin rash consisting of small fluid-filled blisters (vesicles) that form scabs and can leave permanent scars. So shingles is sometimes called herpes zoster. a rash around the eye. 17842. Acyclovir isn’t absorbed as well as valacyclovir, so it has to be taken more frequently. Background. Shingles on face. Inflammation (day 1): Swelling and redness. Because stress weakens the immune system, and a weakened immune system is a risk factor for shingles, some experts believe that stress indirectly triggers. If you’ve ever had chickenpox, you can get shingles. 1 percent) as a long-term agent to minimize the risk of elevated IOP. Varicella (Chickenpox) Herpes zoster (Shingles) Herpes zoster ophthalmicus. Primary HSV infection is identified in only one-third of patients. Synopsis. This topic will address the epidemiology, clinical. Shingles. Shingles: Along with antiviral medicines, you can use calamine lotion for shingles. [1] This occurs because the nasociliary branch of the. Ramsay Hunt syndrome occurs when the varicella-zoster virus reactivates in the facial nerve, which is the cranial nerve that affects your face, tongue and inner ear. About WikEM; Disclaimers; This page was last edited 07:01, 5 June 2015 by Neil Young. It is the same virus that causes chickenpox. Shingles causes a painful, itchy, and blistering rash. Roughly 30% to 60% of people over age 60 who get shingles go on to develop a chronic pain syndrome called post-herpetic neuralgia. Sometimes itches. Cytomegalovirus. Shingle Type: Hip & Ridge. Joint pain. Vesicles (fluid-filled sacs) are tingling and. Herpes zoster (shingles) is caused by the herpes zoster virus and is characterized by pain and unilateral vesicular rash that typically affects one dermatome. You will typically develop a rash about 1-5 days after you feel numbness or tingling pain. Severe infections may require intravenous (IV) treatment. Recurrence: 400mg PO TID x 5 d. PHN is a complication of shingles characterized by long-term nerve. [2] WikEM initially started as a database created from notes and checklists passed from resident class to subsequent resident class at the Harbor-UCLA emergency. Diagnosis: Shingles (Herpes Zoster) Background: Shingles, also known as herpes zoster, is the result of reactivation of the varicella-zoster virus (VZV) and is estimated to occur in more than 1. Herpes zoster (shingles) is a reactivation of latent infection of varicella-zoster virus (VZV). You need 2 doses, with the second dose given 2 to 6 months after the first. fever and chills. It is estimated that the lifetime risk of HZ is 30%, and 1 million new cases are reported annually in the United. Physicians must be aware of risk factors and treatment modalities. Look at palms, soles and mucous membranes. Shingle Type: 3-tab. If your shingles rash has not yet scabbed over, you may need to avoid activities that put you in contact with others. Herpes zoster (Shingles) Herpes zoster ophthalmicus; Herpes zoster oticus (Ramsay Hunt syndrome) HHV-6 (Roseola infantum) HHV-8 (Kaposi’s sarcoma) Epstein-Barr virus; Cytomegalovirus; Clinical Features. Herpes gingivostomatitis of mouth. Following primary infection, VZV remains dormant within the dorsal root ganglia and may reactivate along the first division of the trigeminal nerve, resulting in ophthalmic manifestations. Various neurologic complications have been reported to occur with herpes zoster, including Bell's palsy, the Ramsay Hunt syndrome, transverse myelitis, transient ischemic attacks,. Ocular involvement in HIV could be caused by opportunistic. The virus can reactivate later in life and cause shingles. Shingles vaccination is the only way to protect against shingles and postherpetic neuralgia (PHN), the most common complication from shingles. Before the rash develops, people often have pain, itching, or tingling in the area where the rash willApril 15, 2019. 1 Herpes Virus Types; 2 Clinical. Authors: Ross Donaldson. Doctors diagnose herpes zoster ophthalmicus. Disseminated zoster most commonly affects immunocompromised patients and only rarely the immunocompetent population. It may remain dormant (not active) and you will not have any symptoms. A rash around the ear, mouth, face, neck, and scalp. It is caused by the varicella-zoster virus (VZV), the same virus that causes chickenpox. These options do not cover gonococcal or chlamydial infections. Complications from shingles can include: Postherpetic neuralgia. Shingles are bound to affect 1 out of 3 adults past the age of 50. Skin rash treatment should prevent bacterial superinfection. Valacyclovir. Herpes zoster is commonly known as shingles. A shingles rash can cause pain, burning, numbness, or tingling of the skin and be sensitive to the touch. VZV can reactivate later in a person’s life and cause herpes zoster. Ringworm. Shingles (herpes zoster) is an infection that causes a painful rash. fever. The CDC estimates that approximately 30 percent of people living in the US will experience shingles in their lifetime 2. This is the same virus that causes chickenpox. Opioids are very strong pain medicines that a health care provider can prescribe. Periorbital swelling. These bumps look different than the. Shingles is a painful rash that usually develops on one side of the body, often the face or torso. This 2017 study suggests that it’s one of the best-tolerated treatments for PHN. Shingles. Crusting (day 5–8): A honey/golden crust starts to. She wears a pink sweater bearing the symbol of Aether. There are more than 1 million. Shingles in the mouth can lead to: Mouth sensitivity. Shingrix is also recommended for adults 19 years and older who have weakened immune systems because of disease or therapy. Lidocaine patches are generally used to help relieve pain. Very rarely, shingles can also. Shingles Vaccine Information Statement (Shingrix)Started at 100mg one to two times per day. Esotropia (eye moves inward) of the affected eye due to the unopposed action of the medial rectus muscle. They grow bigger and pop open. Central Nervous System Infections. Chickenpox in adults and immunosuppressed people can be severe. Once. itching and burning sensations. Herpes zoster, or shingles, is caused by reactivation of varicella zoster virus, which causes chickenpox. Human Immunodeficiency Virus (HIV) is a retrovirus which causes a multisystemic disease called Acquired Immune Deficiency Syndrome (AIDS). burning, pain, or tingling in the mouth. However, you can have shingles more than once. Side effects are slightly more common after the second dose of Shingrix. If you get shingles after being vaccinated, the symptoms can be much milder. Funds go solely to hosting and development costs that allow medical practitioners around the globe to freely access WikEM. Diet. The two ingredients can soothe itchy skin from shingles. About 98% of US adults have had chickenpox and are at risk for shingles. At first, the rash looks like little bumps. After you recover from chickenpox, the virus moves to nerves inside your body, where it goes to sleep. About 30% of people in the hospital for shingles have a weakened or suppressed immune system. Varicella zoster virus. Several antiviral medicines are available to treat shingles: Acyclovir (ay-sah-EE-kluh-veer) Valacyclovir (va-luh-sah-EE-kluh-veer) Famciclovir (fam-sah-EE-kluh-veer) These medicines shorten the length and severity of the illness. Share this article via email. Up to half of cases manifest corneal complications. Herpes zoster, or shingles, is a common infection caused by the reactivation of varicella zoster virus that lies dormant in the dorsal root nerve ganglion following primary chickenpox infection. Shingles can develop only after initial infection with chickenpox, or, more uncommonly, after vaccination for chickenpox. Blister outbreaks may be rare or happen when you're stressed or immune-compromised. 1007/s11916-016-0548-x. Caused by Varicella Zoster Virus (VZV) causing Varicella (chicken pox) and later zoster (shingles) Virus is dormant in dorsal root ganglion and reactivates causing characteristic rash in dermatomal distribution Occurs once immunity to virus declines (elderly, immunosuppressed, post transplant, HIV) Clinical FeaturesBackground. If the shingles rash appears around the eye or forehead, it can cause eye infections and temporary or permanent loss of vision. Shingles, or herpes zoster, is an infection that can develop after a person has chickenpox. org Herpes zoster (Shingles) Herpes zoster ophthalmicus; Herpes zoster oticus (Ramsay Hunt syndrome) HIV associated conditions. Skin conditions like psoriasis, eczema, or an allergic rash can be mistaken for shingles by some, but rarely by health professionals who know what to look for. Unfortunately, these oral shingles blisters can be painful and take up to four weeks to heal. 1 / 4 . The shingles rash commonly occurs on one side of the torso. Herpes zoster, or shingles, is caused by reactivation of varicella zoster virus, which causes chickenpox. The branches of the trigeminal nerves are affected in up to 20% of. Shingles, also called herpes zoster, is an infection caused by the same virus that causes chickenpox. 5 times greater risk of stroke than controls. Oral analgesia; Antiviral Options. 2 million Americans. Roseola infantum. After the primary infection, the patient is immune to the virus, which then lies inactive in the dorsal root ganglia or cranial ganglia. Herpes Simplex Virus-2 (Redirected from HSV-2) Contents. multiple painful lesions; no buboes (occasionally shoddy lymphadenopathy) more common in Black patients Shingles. Shingles (Herpes Zoster) About 1 out of every 3 people in the United States will develop shingles, also known as herpes zoster, in their lifetime. Herpes zoster. " Acute herpes zoster typically presents with a rash that is painful but self-limited. Genital/Mucocutaneous HSV. Redirect page. In app subscription purchases: *The in-app purchase unlocks personalized lists and favorites for 1 year. headache. Preeruptive Stage. About WikEM; Disclaimers; This page was last edited 13:02, 30 September 2014 by Ross Donaldson. This is the same virus that causes chickenpox. Use of Recombinant Zoster Vaccine in Immunocompromised Adults Aged ≥19 Years: Recommendations of the Advisory. Standard Western medical care is antivirals in the acyclovir family and for the subsequent neuralgia, Neurontin (gabapentin). In case of recurrence, increase the steroids and lengthen the taper. On the low end, aluminum costs about $4 to $11 per square foot, and on the high end, copper costs $15 to $30 per square foot. CDC. g. Herpes zoster optic neuritis (HZON) is a rare sequela of herpes zoster ophthalmicus (HZO), It can occur either in conjunction with HZO or, more frequently, presents as a postherpetic complication, and has been reported up to 10 weeks after HZO onset. However, immediate shingles treatment — often including an antiviral drug, such as acyclovir (Zovirax), famciclovir or valacyclovir (Valtrex) — can reduce pain, speed healing and reduce the. 1 Partial Seizures; 2. The varicella-zoster virus, which causes chickenpox, can lie dormant in the nerve cells until years. The rash most commonly occurs in a band pattern on one side of. INTRODUCTION — Herpes simplex virus type 1 (HSV-1) is a cause of recurrent vesiculoulcerative lesions of the oral or genital mucosa. Following primary infection, VZV remains dormant within the dorsal root ganglia and may reactivate along the first division of the trigeminal nerve, resulting in ophthalmic manifestations. It typically shows up on only one side of your body. The rash can appear red, dark pink, dark brown, or purplish, depending on your skin tone and typically occurs on one side of. S. Hutchinson's sign is a clinical sign which may refer to: Hutchinson's pupil, an unresponsive and enlarged pupil on the side of an intracranial mass. Allergic Rash. Undressing the patient to fully examine the trunk and the extremities. The ranges of motion that are typically abnormal. If the shingles virus attacks the ear, people may develop. Herpes zoster inflames the sensory root ganglia, the skin of the associated dermatome, and sometimes the posterior and anterior horns of the gray matter, meninges, and dorsal and ventral roots. It is a member of the same family (Herpesviridae) as herpes simplex. The rash begins with reddish bumps. Herpes zoster (Shingles) Herpes zoster ophthalmicus Herpes zoster oticus (Ramsay Hunt syndrome) HHV-6 ( Roseola infantum) HHV-8 ( Kaposi’s sarcoma) Epstein-Barr virus Cytomegalovirus Clinical Features Differential Diagnosis Evaluation Workup Diagnosis Management Disposition See Also External Links References Genital HSV 1st episode: 1000mg PO BID x 7-10 days, start within 48-72 hour of symptoms recurrence: 500mg PO BID x 3 days, alternative: 1000mg PO qday x 5 days Shingles 1000mg PO TID x 7 days Pediatric Dosing Genital HSV ≥12 yrs same as adult dosing for adolescents Special Populations Pregnancy Rating: B Lactation: Excreted in breastmilk Drug rash. Joint pain. Sometimes people feel a little bit tired, with. An eczema rash. 1, 2021, in the Journal of the American Academy. The vaccine helps reduce your risk of getting shingles. In a patient with a winged scapula, the medial or lateral aspect of the scapula appears to be protruding from the back. Witch Hazel. PCR is the most useful laboratory test for confirming cases of herpes zoster. Caring for the skin with shingles can include steps such as keeping the skin clean and covered, applying cool compresses, taking oatmeal baths, and wearing loose-fitting clothing. Shingle Color: Gray. This is the same virus that causes chickenpox. tingling. Physicians must be aware of risk factors and treatment modalities. When it involves the region that surrounds your eye, it is called herpes zoster ophthalmicus and can cause serious eye problems including corneal. 2 / 4 . Herpes zoster (Shingles) Herpes zoster ophthalmicus; Herpes zoster oticus (Ramsay Hunt syndrome) Evaluation. The CDC recommends people ages 50 and older get the Shingrix vaccine to protect against shingles. An injury or lesion in either pathway may result in changes in pupil size. Contents. Shingles refer to a painful rash that the herpes zoster virus causes. Other effects include: Many people who get the vaccine have muscle aches, headaches, or feel tired. 25 BCE to c. Bell's palsy causes most cases of acute, unilateral facial palsy; infection with herpes simplex virus (HSV) type 1 may be its major cause. They monitor the effectiveness and impact of the vaccination campaign. The same virus that causes chickenpox also causes shingles. Both viruses are able to lie dormant within the. Oral. Shingles, or herpes zoster, is a painful rash caused by the varicella-zoster virus (VZV). Cytomegalovirus. Caused by varicella zoster virus (VZV; also known as Human Herpes Virus 3) causing Varicella (chicken pox) and later zoster (shingles) Virus is dormant in dorsal root ganglion and reactivates causing characteristic vesiculopapular rash in dermatomal distribution. Also known as shingles. The varicella-zoster virus is a member of the herpesvirus family (herpesvirus type 3). Most of these infections involve the oral mucosa or lips (herpes labialis. Shingles is a rash that can affect people who have had chickenpox, even if they had it years ago. However, you can have shingles more than once. This is intrinsically suspicious as the formal evaluation and detection of relatively low levels of odour particles is itself a very tricky task in air epistemology. The rash may instead involve the face, eyes, mouth, and ears. About 10% to 18% of people who have shingles develop nerve pain that lasts for months or years after the rash goes away. Doctors diagnose herpes zoster ophthalmicus. Herpes zoster only develops in people who have had chickenpox in the past. CDC recommends that adults 50 years and older get two doses of the shingles vaccine called Shingrix (recombinant. Herpes zoster oticus (Ramsay Hunt syndrome) HHV-6 ( Roseola infantum) HHV-8 ( Kaposi’s sarcoma) Epstein-Barr virus. itching. Herpetic whitlow. The shingles rash develops into painful blisters that may also be itchy, usually on one side of the body, either on. Find My Store. Apply the lotion directly to your skin to get some relief from the symptoms of this condition. Next, a rash of macules, which might look like. Sometimes itches. Shingles . Shingles is somewhat more common among females than males. Swollen glands (lymph nodes) You may also have pain, muscle weakness, and a rash involving different parts of your face if shingles affects a nerve in your face. But even a. Postherpetic neuralgia after herpes zoster can considerably affect quality of life. The side effects of Shingrix may last for a few days but are not serious. Bilateral red eyes. Herpes zoster (HZ) uveitis is caused by the reactivation of the varicella zoster virus (VZV), a double-stranded DNA virus of the Herpesviridae family. Chronic allergic conjunctivitis. Herpes zoster (Shingles) Herpes zoster ophthalmicus; Herpes zoster oticus (Ramsay Hunt syndrome) HHV-6 (Roseola infantum) HHV-8 (Kaposi’s sarcoma) Epstein-Barr virus; Cytomegalovirus; Clinical Features. When the eye is quiet, slowly taper the dose over weeks or months. Older adults and people with weakened or suppressed immune systems are more likely to need to go to the hospital. Varicella zoster virus. Symptoms improve in nearly all patients. This is the same virus that causes chickenpox. Funds go solely to hosting and development costs that allow medical practitioners around the globe to freely access WikEM. Shingles is sometimes called herpes zoster. Immunizations are very important for adults to prevent illness and remain healthy. Drug rash. Shingles is caused by the varicella-zoster virus. Many vesicular rashes will improve on their own or with home treatment. It is more common in people with weakened immune systems, and in people over the age of 50. This soothing bath may help calm your. Reactivation of the virus usually occurs in a single nerve, leading to the symptoms of. Unilateral red eye. Genital herpes is most often caused by the HSV-2 virus, but can also be caused by HSV-1. Post-herpetic Neuralgia: a Review. Management General treatment. Shingles is a viral infection that can cause a painful rash. Shingled magnetic recording (SMR), a magnetic storage data recording technology used in hard disk drives. 9 cases per 100,000 live births. The CDC recommends that all healthy adults ages 50 and older get two doses of the shingles vaccine, separated by two to six months. Genital HSV 1st episode: 1000mg PO BID x 7-10 days, start within 48-72 hour of symptoms recurrence: 500mg PO BID x 3 days, alternative: 1000mg PO qday x 5 days Shingles. Cefotaxime 50mg/kg IV q6hrs OR Gentamicin 2. Lidocaine patches are easily found over the counter at your local pharmacy. Eczema herpeticum; Herpes gingivostomatitis; Herpes keratitis; Herpes labialis (cold sore. INTRODUCTION — Herpes simplex virus type 1 (HSV-1) is a cause of recurrent vesiculoulcerative lesions of the oral or genital mucosa. Herpes simplex virus type 1 (HSV-1) encephalitis is the most common cause of sporadic fatal encephalitis worldwide. Funds go solely to hosting and development costs that allow medical practitioners around the globe to freely access WikEM. Temporary or permanent paralysis of one side of the face (similar to Bell palsy. In addition to the rash, shingles can cause fever, headache, chills, or upset stomach. Shingles can occur anywhere on your body. It’s the same virus that causes chickenpox. ↑ Somand D, Meurer W. Product Warranty: 25-year limited. Even children can get shingles. Counsel patient/family on importance of hand hygiene/avoiding touching face to prevent spread! Apply warm or cool compresses (for comfort and cleansing) every 4 hours, followed by instillation of ophthalmic antibiotic solutions. The symptoms of shingles include: Localized burning, tingling, itching, prickling pain that starts days to weeks before the rash appears. Rubella (German measles)This is particularly true for herpes zoster ophthalmicus (HZO), a 2016 Academy policy statement said. Clinical Findings. Once a person has chickenpox, the virus stays in their body. Shingles, also known as herpes zoster or just zoster, occurs when a virus in nerve cells becomes active again later in life and causes a skin rash. The disease may be manifested as a toothache during its prodromal. In the United States, there are around one million cases of HZ per year. burning or shooting pain at the rash site. Home remedies for shingles can provide relief from symptoms although they won't cure you of the condition. Shingle(s) may refer to: . This abnormal position of the scapula can lead to many physical functional disabilities such as pain, decreased strength, and range of motion. Treatment includes. Aveeno Anti-Itch Concentrated Lotion contains a combination of calamine and oatmeal. Shingles is contagious. Medical therapy. Shingles is caused by the varicella-zoster virus — the same virus that causes chickenpox. The efficacy of VALTREX when initiated more than 72 hours after the onset of rash and the efficacy and safety of VALTREX for treatment of disseminated herpes zoster have not been established. Epstein-Barr virus. Will Shingles Come Back? 8 million+ Physician Ratings & Reviews. Starts on trunk or scalp as pruritic, red macules, spreads to extremities. numbness and tingling. Ten percent of HZ cases are subtyped as herpes zoster ophthalmicus (HZO) specifically and involve the V1 distribution. Shingles. Treatment. gastrointestinal symptoms. Immunizations: Shingles (Herpes Zoster) Shingles is an infection caused by the varicella-zoster virus. Wald. sensitivity to touch. Overview. Eczema. Vaccines are available for prevention of both infections. About 1 in 4 people have a. The usual acyclovir dose for shingles is 800 mg by mouth 5 times a day for 7 to 10 days. Background Early intervention reduces the incidence of postherpetic neuralgia (PHN). It is estimated to affect at least 1 in 500,000 individuals per year, and some studies suggest an incidence rate of 5. Varicella-zoster virus (VZV) is the causative agent of varicella, or "chickenpox," and herpes zoster, or "shingles. Herpes zoster ophthalmicus is a reactivated infection of the eye caused by the varicella-zoster virus, the virus that causes chickenpox and shingles . Genital herpes is most often caused by the HSV-2 virus, but can also be caused by HSV-1. Background. 23. WikEM, The Global Emergency Medicine Wiki, is the world's largest and most popular emergency medicine open-access reference resource. Postherpetic neuralgia is a complex neuropathic pain condition in which the pain is. Fluid-filled blisters that break open then scab over. Background Herpes zoster, also known as shingles, results from reactivation of the varicella-zoster virus. It can re-emerge years or. PMC4208116. Paralysis of facial nerves. It's recommended for people at higher risk from shingles, including all adults turning 65, those aged 70 to 79 and those aged 50 and over with a severely weakened immune system. muscle weakness. 1136/bcr-2013-200101. This discomfort typically occurs a few days before the visible rash develops. The most common early symptoms occur on one part of the body or face. Herpes zoster (HZ), or shingles, results from reactivation of latent infection with varicella- zoster virus, which also causes chickenpox. Shingles is characterized by a severely painful, itchy, or tingling rash, most commonly on one side of the torso, although it can occur anywhere on the body. CDC recommends two doses of recombinant zoster vaccine (RZV, Shingrix) to prevent shingles and related complications in adults 50 years and older. Shingles, also known as herpes zoster, is a disease that results from the reactivation of the varicella-zoster virus (VZV). Self-care is an important step in managing the symptoms. Shingles, also known as Herpes Zoster, are a contagious viral illness that results in a painful rash. Primary HSV-1 infection of lips, gingiva, and tongue. Baking soda and cornstarch paste. CertainTeed. Some Medicaid plans: Contact your insurance provider to find out if your plan covers the shingles vaccine. Herpes zoster, also known as shingles, results from reactivation of latent VZV that gained access to sensory ganglia during varicella. Primary infection with VZV causes varicella. If you've had chickenpox, the virus can lie dormant in your body's nerve tissue for years when suddenly it's triggered by stress or a weakened immune system, and manifests as shingles. This topic will address the use of the two vaccines used to prevent herpes zoster.